Sentence examples for aging hallmarks from inspiring English sources

These data clearly indicate that altered intercellular communication as one of the aging hallmarks is of central relevance for the development of BPD and most likely contributes to long-term consequences as the lung matures and ages.

Again, several networks relevant to aging hallmarks were readily grouped together.

We have recently added an additional hallmark to these molecular pathways, i.e., dysregulation of the ECM, and dissected the distinct aging hallmarks for their differential contribution to the development of age-related chronic lung diseases such as chronic obstructive pulmonary disease (COPD), lung cancer, and idiopathic pulmonary fibrosis (IPF) [12].

Further proteomics analysis unraveled molecular networks related to diverse aging hallmarks, suggesting the broad utilities of our cellular model for mechanistic dissection of NSC and neural aging.

Our findings of reduced autophagy (either at the induction level or any step before autolysosome formation) contributes to the overall cellular aging hallmarks, and to the notion that this may be due to lower autophagic capacity in aging cells.

Another aging hallmark is deregulated nutrient sensing via the IGF-1/AKT/mTOR axis, an evolutionary conserved growth signaling pathway that integrates nutrient signals to regulate cell growth [48].

But Dunph does it his way and goes back home on his own terms in a film that "doesn't have the time or piety for the usual coming-of-age hallmarks" (Maslin).

Consequently, the third generation of mTerc−/− mice (G3 mTerc−/−) showed premature aging phenotypes hallmarked by gray hair, humped back, compromised fertility, and decreased life span (Herrera et al., 1999).

"I don't care what anybody thinks/I've released that fear," Ms. Hudgens sings about the end of a traumatic relationship or, lyrical ambiguity being a coming-of-age hallmark, the transition from child star to adult maybe-star.

While there's little debate that the enormous burden of aging is a hallmark of our time, it's mainly regarded as an inevitability by most people and by uber-cautious federal agencies that fund research and green-light drugs.

He measured scores of molecules in the blood, hoping to find clues that would lead him to the cause of aging's hallmarks, particularly sarcopenia, or loss of muscle mass, and cognitive decline.