The phrase "aging escalation" is not commonly used in written English and may not be immediately clear in meaning.
It could be used in contexts discussing the increasing effects or challenges associated with aging, particularly in fields like healthcare or social policy.
Example: "The aging escalation in our population presents significant challenges for healthcare systems as they struggle to meet the needs of an older demographic."
Alternatives: "aging increase" or "age-related growth".
This is relevant, as the impact of age becomes increasingly important with age escalation.
With the escalation of the aging population worldwide, dementia has become a major public health concern.
2 Old age (or the older adult) is defined as the age of 65 or older, and the last century had seen escalation in the aging population.
Other books of Brodie's dealing with nuclear strategy include The Atomic Bomb and American Security (1945), Strategy in the Missile Age (1959), Escalation and the Nuclear Option (1966), and From Crossbow to H-Bomb, which he wrote in 1973 in collaboration with his wife, Fawn M. Brodie, a prominent historian.
Along with population growth and ageing, the escalation in mortality rates means that the component of change in deaths due to risk is large; in female subjects, it is responsible for a 50.5% increase in lung cancer deaths, and a 54.8% increase in breast cancer by 2000, a change that exceeds the contribution due to population growth and ageing (Table 3).
In paediatric patients (aged <16 years), dose escalation to >30 mg/kg per d significantly reduced serum ferritin levels by 617 μg/l compared to the levels prior to dose escalation (P< 0·0001, n= 111; Table III).
In fact, 2009 saw an escalation in interest in microRNAs and other non-coding RNAs implicated in aging and replicative senescence.
The age de-escalation approach is often used in testing pediatric vaccines but "had not been discussed" for the anthrax vaccine, said commission member Christine Grady, bioethics chief at the National Institutes of Health's Clinical Center in Bethesda, Maryland.
The trial reported here is the next in a series of age de-escalation steps towards the EPI age range, contributing to adjuvant and schedule selection.
RTS,S/AS01E proved similarly as well tolerated and immunogenic as RTS,S/AS02D, completing an essential step in the age de-escalation process within the RTS,S clinical development plan.
