The phrase "aging depletion" is not a standard expression in written English, but it can be understood in context.
It may be used in discussions related to the decline of resources or capabilities as one ages, particularly in fields like biology, medicine, or economics.
Example: "The study focused on the effects of aging depletion on cognitive functions in older adults."
Alternatives: "age-related decline" or "senescence depletion."
It suppresses cancer, a major aging-related disease, but contributes to other, non-cancer, degenerative aging phenotypes through depletion of cells, including stem cells.
A diminished capacity to maintain tissue homeostasis is a central physiological characteristic of aging, and the depletion of stem cell reserves and/or diminished stem cell functions have been postulated to contribute to aging.
A notable difference exists in the case of IIS and TGF-β mutants where fat levels remain extraordinary low during aging upon PHB depletion.
Thus, chemical menopause may be a better option to examine interactions of aging with estrogen depletion rather than the loss of all ovarian hormones as would result from ovariectomy.
This would explain our observation of less neuron loss with GSH depletion than with NAD(P H depletion in aging and AD.
These opposite effects might reflect differences between the two distantly related yeasts and/or between the two distinct chronological aging models involving glucose depletion in budding yeast and long-term quiescence on nitrogen depletion in fission yeast.
Zn solute enriched at the subgrain boundaries in the ASL, and was depleted in the matrix solid solution of the ASL after 60 months of natural aging, but depletion of Cu was not evident on AA7055-T6.
For decades, the difficulty older women faced in becoming pregnant was attributed primarily to two factors: the declining frequency of intercourse among older couples and the aging and depletion of a woman's eggs, all of which were believed to be present when a girl is born.
FGF-2, which often functions as a mitogen, was recently reported to contribute to the aging and depletion of mouse satellite cells.
Add to that resource depletion, globalization, aging populations, climate change and the accelerating speed of technological change and adoption – from mobile phones to social media and Internet connectivity.
