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It was a time when experts pinned their hopes on quick development of a vaccine instead of aggressive, large campaigns to stress other prevention measures like H.I.V. testing, safe sex and condom use.
It often presents as an aggressive, large, high grade sarcoma of the extremity.
In this review, we will take a close look at some of the more intriguing targets in aggressive large B-cell lymphomas, all of which now have small molecules that can profoundly affect their activity, activity we hope will lead to new treatment opportunities.
Moreover, S100A6 hypermethylation was significantly associated with the aggressive large cell/anaplastic morphophenotype (P= 0.026).
More recently, it has been shown that NR4A1 (Nur77) expression was significantly associated with poor survival in patients with aggressive large B-cell lymphoma [ 24].
This finding might explain why most of the patients we encountered had aggressive (large, multiple, and disfiguring facial lesions) and prolonged disease courses necessitating treatment with intramuscular rather than intralesional medication.
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By the time she was born, certain Inuit traditions had ended or assumed new forms after prolonged contact with an aggressive larger world.
The 1980s, especially in New York but also in cities from Cologne to Tokyo, was a period of media excess and frenzied stock market speculation, typified by aggressive large-scale painting that sold for lots of money.
Our study suggests that immunohistochemical staining with Survivin antibodies may be a useful tool to identify the more aggressive large-cell-anaplastic subtypes.
However, the excess of HD could be because of the evolvement of CLL into aggressive large-cell lymphoma (Richter's transformation/syndrome), often resembling HD (Robak 2004; Schollkopf et al, 2007).
So the WTA decoder chooses a more aggressive (larger) scale ratio that improves precision, without being penalized by increased ambiguity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com