Exact(1)
Shouting out harsh criticism was his way of taking the measure of a room, Catmull says: "Steve used aggressive interplay as a kind of biological sonar.
Similar(59)
Although the precise mechanisms for LRP1 in malignancy remain controversial, accumulating evidence of its role in cancer progression encourage further studies on the interplay between an aggressive phenotype and uptake of ANG1005 and other EPiC agents.
Utilizing multiple structures that stand in more flexible interplay [ 21, 51, 52] cold aggressive behaviors are similar to other forms of instrumental behaviors, such as deceit, which appears to draw widely on diverse brain resources to accomplish a very complex task.
Besides its pivotal role in controlling transcription as a cofactor of CSL (CBF1/RBPJ-κ /Su(H) Lag1) family of DNA binding proteins, the ability of Notch to endow breast cancer cells with aggressive and stemness features results also from the interplay with several pathways, among them PI3K/Akt, Jak/STAT, NF-kappaB, ErbB2, Wnt, and HIF1 (Ranganathan et al, 2011).
Esophageal cancer is an extremely aggressive gastrointestinal malignancy, which appears to result from a complex interplay between genetic and environmental agents.
The connection between alcohol consumption and aggressive behaviour operates at multiple levels and is the result of a dynamic interplay among personal and socio-environmental systems [ 23].
These findings would support the 'transformation hypothesis' that proposes that FLSs/MSCs become transformed by the chronic interplay with the inflammatory processes in the joint, resulting in a more aggressive cell type with the ability to invade the articular cartilage, as demonstrated in models of co-implantation of normal cartilage and RA FLSs in vivo in mice [ 26].
Mounting evidence indicates that the acquisition of an aggressive cancer phenotype through EMT, as well as other cellular events, may be understood by evaluating the regulatory interplay between TFs and miRNAs [ 12, 13].
Deregulation of E2F activity and early cell cycle progression has also been implicated in aggressive prostate cancer (Sharma et al, 2010), but the precise role of E2Fs in cancer is dependent on a balanced interplay with other regulatory factors and these interactions in prostate cancer need to be elucidated.
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The interplay is all.
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