In the aggressive control of hypertension, the mantra of "lower is better" was mostly based on the landmark randomized clinical trials (RCTs) published in the 1990s (8– 10) that established clear benefit with regard to cardiovascular risk reduction when blood pressure was lowered intensively in patients with diabetes.
The Turkish government's lifting of the ban on head scarves in government offices, including teaching positions (news article, Oct. 9), is a welcome and long-awaited change for millions of Islamic women in this Muslim country and an important remedy for Turkey's overly aggressive control of religion in the name of secularism.
This single and systematic design methodology is shown to achieve the semi-global ultimate boundedness of the closed-loop helicopter dynamics and accommodate the aggressive control of flight maneuvers from hovering to trajectory tracking.
And while there are many critics of the Kremlin's aggressive control of big business, Putin has created a measure of economic stability.
Early diagnosis of APS through examination of the heart and aggressive control of all traditional risk factors through lifestyle modifications and pharmacotherapy, probably anti-inflammatory treatment, and close follow-up of APS patients may help to minimize CV risk in these individuals [ 189, 193].
Given these currently noncomorbid patients in this cohort only had modest increases in BMI, the early and aggressive control of weight should be a focus for intervention.
The 2001 study of Van den Berghe and colleagues demonstrating important benefits of intensive insulin therapy in critically ill patients [ 1] led to the hypothesis that aggressive control of hyperglycemia in patients with acute stroke could limit brain damage and improve clinical outcome.
Until safe and effective agents become available to lower A1C to <6.2%, reducing albuminuria by aggressive control of multiple risk factors, notably blood pressure and inhibition of the renin-angiotensin system, is of critical importance to reduce the risk of stroke in type 2 diabetes.
In the ACCORD trial, rapid and aggressive control of glucose was associated with significantly increased risk of death from cardiovascular disease, although this finding was not supported by the ADVANCE study.
