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Tumors with similar cell phenotypes, classified with the same IPI score, could have different capacities for active liberation of mRNA into plasma, which could be interpreted as a more aggressive characteristic of some of these lymphomas.
Notably, DU145 cells aberrantly expressing LEDGF or overexpressed with LEDGF displayed enhanced and aggressive characteristic features of tumorigenicity.
Presented articles showed that some cytokines may contribute to the aggressive characteristic of ESCC and correlate with primary tumor progression, lymph and distant metastasis, and patients outcome.
More recently it has been shown by IHC analysis that S100A10 expression in thyroid neoplasms contributes to the aggressive characteristic of anaplastic carcinoma (Ito et al, 2007).
Also, Ito et al. demonstrated that preoperative vocal cord paralysis may be a sign of a biologically aggressive characteristic; nevertheless, it does not have a significant prognostic value in this study [ 16].
Because of highly aggressive characteristic, disappointing surgical resection and chemo-radiotherapies, and poor prognosis of the patients with GBC, novel adjuvant therapies or anticancer agents are clearly needed to treat this disease [ 1- 12].
Similar(53)
Six were female, and they exhibited many of the same disturbed, aggressive characteristics of the males.
The term thus implied not only such qualities as are associated with the modern word humanity understanding, benevolence, compassion, mercy but also such more aggressive characteristics as fortitude, judgment, prudence, eloquence, and even love of honour.
In addition, Hanaoka et al. reported that lung cancer patients with pulmonary bullous disease have a poor prognosis because their disease is advanced at the time of detection and because the tumor has aggressive characteristics [11].
Transformation and development of metastasis require stepwise acquisition of aggressive characteristics.
The findings support the hypothesis that vitamin D may reduce risk of the development of a subset of tumors with more aggressive characteristics and poorer prognosis.
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