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Our results suggest that migration has greatly influenced the genetic structure of northern fur seal breeding aggregations, probably both historically (through population expansion since the last glacial maximum) and more recently (through post-harvest expansions and contemporary migrations).
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In addition, a subset of oligonucleotides induced platelet aggregation, probably through their interaction with membrane receptors.
This different mode of aggregation probably causes the differences in stability and tightness of FAD cofactor binding between the DAAOs from different sources.
When the reaction was done at 28 °C, it reached equilibrium after 1 h and was stable over 30 days with no evidence of aggregation probably due to the stabilizing protein coat.
This shows actual increase in protein aggregation, probably due to co-aggregation of truncated αA-crystallins with αAwt.
This aggregation probably is a consequence of conformational changes induced in Fn upon BBK32 or anastellin binding.
In contrast, inhibitory effects of 5′-nucleotidases on platelet aggregation probably occur via catalytic activity that causes the degradation of ADP, a platelet aggregation agonist [ 6].
TIAF1 aggregation probably occurs in the hippocampus in the beginning followed by A β deposition, and that TIAF1 is likely to protect the formation of A β aggregates.
This aggregation probably expelled the trapped drug out of the nanoparticles and drug release was enhanced and consequently RE24% was increased.
In addition, the A30P mutation appears to affect αS independently of protein aggregation, probably by partially impairing the ability of αS to bind to brain vesicles, likely due to a decreased likelihood to form α-helices [ 30, 52].
In addition, type II collagen fibres in the cartilage of CSGalNAcT1-null mice also showed abnormal aggregation, probably due to a reduction in CS, indicating that this enzyme also affects the ultrastructure of cartilage during development.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com