On day 1, peak final-extent IPA was observed 2 to 4 hours after ticagrelor administration, whereas clopidogrel only minimally inhibited platelet aggregation (mean percentage IPA < 20% at all time points).
In contrast to aggregate stability and irrespective of pre-event re-aggregation, the percentage of coarse fragments in post-event FSDs continued to decrease from event to event, suggesting that in addition to the previously re-formed aggregates also new coarse aggregates were broken down.
The gallic acid hybrid GA2 as well as the 2-chromonecarboxylic acid hybrids CA1 and CA2 prevented the self-mediated Aβ aggregation with percentages of inhibition ranging from 53% to 59%.
The % aggregation was the percentage of aggregated cells among the GFP-positive cells which transfected cells.
However at a pH of 6.8, the percentage aggregation increases to about 85%.
The sample is then analysed through a turbidometer, the change in turbidity is recorded and percentage aggregation is calculated.
The rate, or slope, of the aggregation is the percentage change of aggregation per minute.
The absorbance or OD values were subsequently transformed into percentage platelet aggregation values, using the light absorbance of PPP and PRP as reference for 100% and 0% aggregation, respectively.
Percentage of aggregation, aggregation rate and lag-time were calculated using AGGRO/LINK®.
The percentage of aggregation upon stimulation with 0.5 U/mL thrombin decreased significantly after partum in all the experimental conditions.
