Sentence examples for aggregation on the cell from inspiring English sources

Overall, our data provide experimental support for the role of toxic protein aggregation on the cell fitness landscape and the evolution of natural protein sequences.

This study aimed to develop a new type of poly(D,L-lactide-co-glycolide) (PLGA -based nanoPLGA -basedor genanoparticleswhich are capable oforvercomingenee deliverytages of polyethylenimine (PEI)- or cationic liposome-based gene carrier, such as the cytotoxicity induced by excess positive charge, as whicharethe aggregation on the capablerface.

Compared to untreated PR8-infected cells, or those incubated with AH, ATA treatment was found to induce viral aggregation on the cell surface (Fig. 8).

17– 19 Notably, Ir2 demonstrated a small degree of aggregation on the cell surface.

Therefore, to study the effects of amylin aggregation on the beta cell, transgenic mice were developed that expressed human (h IAPP under control of the insulin promoter.

Moreover, PAMAM dendrimers can induce multivalence effects, similar to the polyvalent interactions in biological systems [47], but any successful PDT methodology in atherosclerosis must avoid drug aggregation on the endothelial cells (Figure 1).

Another important issue concerns the effect of hPrP90-231 aggregation state on the cells' ability to internalize the fragment.

In vitro experiments with osteoblast cells indicated an appropriate penetration of the cells into the scaffold's pores, and also the continuous increase in cell aggregation on the bioactive scaffolds with increase in the incubation time demonstrated the ability of the scaffolds to support cell growth.

We examined the impact of such particle aggregation on the cytotoxicity by exposing the cells to NPs under different treatment modalities: short incubation (2 h) in serum-free medium or long incubation (24 72 h) in serum-containing medium.

This suggests that majority of the Aβ aggregation seems to take place on the cell surface rather than intracellularly.

This review explores how introducing the dimension of circadian time and the circadian clock might refine the analysis of aberrant aggregation, thus expanding our perspective on the cell biology common to neurodegenerative diseases.