Sentence examples for aggregation of peptides from inspiring English sources

It has been suggested that aggregation of peptides and proteins is generally promoted by hydrophobicity as such [37], [38], because hydrophobic regions of peptides and proteins are known to be crucial for triggering the aggregation process and to form the core of fibrils [37], [38] including the Aβ fibril [16], [39].

Recent reports describe the aggregation of peptides due to repeat-associated non-ATG (RAN) translation (Mori et al., 2013b) as previously described in SCA8 (Zu et al., 2011).

Primary and secondary aggregation of peptides and proteins disrupt normal protein homeostasis, leading to pathological states involving aberrant protein aggregation [ 76– 76].

As a result of aggregation of peptides in the cytoplasmic membrane, channels are formed which destabilize bacterial membranes thus leading to microbial cell death (Chrzanowska 1998).

The barrel-stave model involves aggregation of peptides at the membrane bilayer; the hydrophobic peptide regions align to form a lipid hole like a barrel, disrupting the osmotic balance of the bacterial inner membrane.

It is believed that the formation A β plaques arises from aggregation of peptides A β40 and A β42, and is the initial event in the pathogenesis of the AD.

It is the Ag+-induced folding structure of the peptides that leads to the aggregation of peptide-AuNPs.

Part 2 of this work widens the scope of this approach by investigating a biopharmaceutical product, as the aggregation of peptide based drugs affects their therapeutic activity and can induce allergic reactions in patients.

The algorithm can actually predict the aggregation propensity of peptides in the presence of cell material [27].

We compared the aggregation states of peptides in water and PBS by examining Trp fluorescence as a function of peptide concentration from 1 to 18 μM.

Solubility of recombinant proteins expressed in E.coli can be predicted by TANGO, an algorithm developed to determine the aggregation propensity of peptides.