Interestingly, glioma cells engineered to express Cx43 formed bigger homocellular aggregates compared to control cells [ 45], suggesting that increased aggregation may be due to increased adhesive properties of the cells as a result of Cx43 expression.
This suggests that aggregation may be partially mediated through other aggregation prone segments in addition to W3238.
Premature aggregation may be prevented by formation of micelles, where the hydrophilic NT and CT domains sequester the hydrophobic and repetitive regions.
Research on aggregation may be helpful to develop a suitable formulation for chA21 clinical application as well as provide direction for future antibody design and reconstruction.
Emulsion instabilities such as depletion flocculation, coalescence, aggregation and heat-induced protein aggregation may be detrimental to the production of sterilised food emulsions.
In this scope, and to reduce the number of transmitted packets to sink node, data aggregation may be effective technique, which is a critical function of WSNs.
This inhibition effect on aggregation may be due to the increased initial crystallinity of the microspheres, which help to maintain the microsphere morphology during EO gas sterilization.
It also seeks to propose that other attributes may be able to be quantified through analogous FOMs (e.g., transformation) and that, with quantification, aggregation may be possible using concepts from the risk community.
The practical consequence of this aggregation may be observed as spurious results associated with receptor-based high throughput screening assays as well as anomalies in phase-solubility analysis encountered in the study of hydrophobic materials with cyclodextrins.
Our results suggest that suitable ES solutions are characterized by high concentrations of peptides, providing backbone physical chain entanglements, and by random coil/α-helical conformations while β-sheet aggregation may be detrimental to spinnability.
Such repulsive interaction and the large changes in fluidity arising from drug aggregation may be related to the disruption of the membrane, which is key for the parasite killing property.
