Sentence examples for aggregation knowledge of from inspiring English sources

In order to prevent α-synuclein aggregation, knowledge of the atomistic structures of possible α-synuclein dimers and the interaction affinity between the dimer domains is a necessary prerequisite in the process of rational design of dimerization inhibitors.

The architecture is composed of three parts: Collaborative Alert Aggregation, Knowledge-based Alert Evaluation and Alert Correlation.

Therapies based on rationally designed aggregation inhibitors require knowledge of molecular structure [ 2]; because of high aggregation tendency of Aβ, it has not been possible to obtain complete structural information by X-ray crystallography.

"We are now in the modern world in the presence of an aggregation of knowledge which no single person can embrace, in all its fullness and diversity.

Unfortunately the control of aggregation is a considerable challenge because the mechanisms of aggregation follow numerous pathways, and although much knowledge of aggregation mechanisms has been accumulated it is still not currently possible to robustly predict a protein's propensity to aggregate [46].

On the basis of the quality by design approach, aggregation of knowledge in process chemistry and manufacturing operations is essential for the continuous development of pharmaceutical products and processes.

He et al. [5] describe two classes of data aggregation approach: Application Dependent Data Aggregation (ADDA), which requires knowledge of application-level traffic flows and Application Independent Data Aggregation AIDAA) which performs aggregation in a generic fashion without application-specific information.

Platforms for the aggregation of knowledge, so called Wikis, are the future.

The aggregation of impacts requires knowledge of (or assumptions about) the relative importance of impacts in different sectors and regions.

We therefore designed and analyzed a large-scale randomized experiment on a social news aggregation Web site to investigate whether knowledge of such aggregates distorts decision-making.

Recent improvements in aggregation predictors rely on using knowledge of native-state protein-protein interactions.