Sentence examples for aggregates positive from inspiring English sources

When such transfected fibroblasts were also exposed to several small molecules (valproic acid, BIX01294 and 5'-aza-2'-deoxycytidine) and cultured in human embryonic stem cell (ES) medium they formed small aggregates positive for alkaline phosphatase activity and OCT4 protein within 30 days.

The percentage of aggregates positive for each factor within each grading group was calculated.

Mutations in the ESCRT-III component VPS2/ chas2beens been found to be associated with neurodegenerative diseases, such as frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), which present proteins aggregates positive both for ubiquitin moiety and the p62 autophagic adaptor protein.

Interestingly, protein aggregates positive for ubiquitin and Ref(2 P show a near complete colocalization with FIP200 and Atg9 in Drosophila mutants lacking more downstream players, raising the possibility that such protein aggregates may serve as an organizing centre during autophagosome formation [ 46, 75].

HMERF patients have features similar to myofibrillar myopathies including myofibrillar lesions and intracellular protein aggregates positive for actin, MYOT and SQSTM1.,, Importantly, experiments performed with Atg7 muscle-specific knockout mice indicated that phosphomimetic NBR1 is able to eliminate pre-existing protein aggregates in vivo.

The pons of alpha-galactosidase A-deficient mice in particular exhibited a striking neuropathological phenotype, including the presence of large, swollen axonal spheroids indicating axonal degeneration, in addition to large interstitial aggregates positive for phosphorylated alpha-synuclein that co-localized with the axonal spheroids.

She keeps in constant contact with her fans on social media, updating her followers on the chart rankings for singles that she's featured on and aggregating positive press in long scrolls and screenshots.

When we spend that much time doing something, even small increases in productivity make a large aggregate positive difference.

If this is the case, there could be an aggregate positive effect of immigration on productivity without one that showed up differentially across plants.

Therefore, the patients were split into aggregate positive and negative patients.

This could indicate that different pathogenic pathways are active in aggregate positive versus negative patients.