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Controlling High Bandwidth Aggregates in the Network.
A protein called alpha-synuclein misfolds and aggregates in the brain in plaques called Lewy bodies.
Another key feature of Parkinson's is the presence of excess alpha-synuclein aggregates in the brain.
Haslebeck, M., Miess, A., Stromer, T., Walter, S. & Buchner, J. Disassembling protein aggregates in the yeast cytosol.
These CamKIIa-hTDP43NLSm mice develop little to no pathological TDP-43 aggregates in the brain even late in their lifespan26.
Ishida, Y. et al. Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection.
The model assumes a simplified distribution of aggregates in the eruption column with a single effective diameter and constant density.
Similarly, the stereotaxic injections in the striatum led to the formation of α-Syn aggregates in the brain.
This protein aggregates in the endoplasmic reticulum, which is the main cause of liver disease in childhood.
A common feature of many human neurodegenerative diseases is the accumulation of insoluble ubiquitin-containing protein aggregates in the CNS.
The viscosity enhancement was caused by the network formation of HA aggregates in the micrometer scale.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com