Hyaline, eosinophilic material was observed in the conjunctiva and nasal mucosa as large aggregates expanding the lamina propria, in a narrow subepithelial zone, in the interstitium of subepithelial glands of the nasal mucosa and around vessels.
The above experiments therefore provide conclusive evidence supporting the previous proposed models [18], [19], whereby glutamine residues in irreversibly aggregated, expanded polyQ stretches, are linked by hydrogen bonds between both main chain and side chain amides.
To improve thermal and acoustic properties on lime cement mortars, fulfilling other physical, mechanical and technical requirements, a gap-graded aggregate (GGA), three lightweight aggregates (LWA) (expanded clay, perlite and vermiculite) and fibers (cellulose and polypropylene) were used.
Fly ash based geopolymer concretes with either quartz aggregate or expanded clay aggregate were exposed to various temperatures up to 750 °C using a thermo-mechanical testing apparatus.
Non-absorbent man-made aggregates like expanded polystyrene (EPS) do not suffer with the disadvantage of water absorption, which makes production of the normal lightweight aggregate concrete difficult.
Additionally, three types of lightweight aggregates including expanded perlite, microscopic hollow ceramic spheres and expanded recycled glass were used as complete replacement of micro-silica sand to reduce density and thermal conductivity of the composite.
At day 5, these aggregates were expanded via adhesion or suspension culture.
Our results suggest that Hsp70 molecular chaperones become trapped by aggregates of expanded PABPN1 in muscle cell nuclei.
This capacity of PSA to reduce the toxicity and accumulation of aggregates containing expanded huntingtin exon 1 and these other disease-associated proteins can be largely attributed to a surprising new function of PSA: its ability to promote protein degradation by autophagy.
