Sentence examples for aggregates demonstrate that the from inspiring English sources

The various spontaneously formed multimeric aggregates demonstrate that, the initially monomeric peptide molecules interact without encountering any major barriers.

Evaluation of Luc GFP during heat stress using GFP fluorescence and immunoblotting of aggregates demonstrated that the decreasing luciferase activity in neurons was associated with an increased incidence of aggregates (Figures 1C, D).

Altogether, these apparent differences between the stress-induced, pathological, and aging-associated protein aggregates demonstrates that protein aggregates are not all equal in their composition or in the way they are being recognized and dealt by the cell and reinforces the importance to discriminate between different aggregation models.

Furthermore, previous studies on age-induced Hsp104 aggregates demonstrated that their asymmetric retention is actin and Sir2-dependent (Erjavec et al., 2007), and that their presence is intimately linked to proteasome function (Andersson et al., 2013).

Our data, in aggregate, demonstrate that LRRK2 directly phosphorylates tau at T149 and T153 in vitro and the ability of LRRK2 to phosphorylate tau at these sites may underlie its ability to promote tauopathy in our novel mouse model.

Thus, 31 (100) means 100% by volume of aggregates with hydrodynamic diameter D H of 31 nm bHydrodynamic diameter of second populations of aggregates The results demonstrate that the associative behavior of the diblock copolymers strongly depends on their composition and on the nature of the solvent used.

Cells and even transmittable genetic aggregates demonstrate properties that can only lead us to conclude that there is a base cognitive level invested in any cell or genetic aggregate as an innate endowment.

In the aggregate, these findings demonstrate that the model is reliably characterized by pleural organization after the induction of pleural infection and enables dissection of local alterations involved in the organizational phase of pleural injury that follows Streptococcal empyema.

In aggregate, these results demonstrate that the FoxO3a-Skp2-p27 FoxO3a-Skp2-p27 FoxO3a-Skp2-p27our in vitro mechanistic experiments in cultured pancreatic cancer cells, associates with the Nupr1−/− genotype in vivo giving rise to OIS with a concomitant impairment in PanIN development.

Under such conditions, the progressive disruption of the interactions involved in the initial NCp7-ssDNA co-aggregates demonstrates that NCp7 molecules bound to nucleic acids are progressively displaced by HIV-1 RT during its tracking along the minus strand DNA template, while re-binding of NCp7 to the dsDNA product is severely impaired (Figure 4).

To demonstrate that the aggregates are formed from F-actin rather than G-actin, cells treated with cucurbitacin I for 4 h were fixed and stained with FITC-phalloidin, which only binds F-actin; the aggregates that were labeled with mCherry-actin were also stained by FITC-phalloidin (Figure 7E).