iRefWeb enables users to examine aggregated interactions for a protein of interest, and presents various statistical summaries of the data across databases, such as the number of organism-specific interactions, proteins and cited publications.
Compared to the domains reported by Dixon et al., our domains tend to aggregate interactions of higher mean frequency, especially at larger γ.
Interaction databases fall into two categories, large-scale interaction repositories, which may aggregate interactions from high-throughput PPI screens from various species and tissue types, and interaction databases that are focused on a specific class of molecules or functions.
The study involves temperature and frequency sweep experiments on unaged and aged asphalt cement (to establish baseline properties), asphalt mastic (to consider physico-chemical aspects), and Fine Aggregate Matrix FAMM – to consider air voids and aggregate interaction effects).
Using STRING interaction information, an aggregate interaction can be computed across units scaling with the sum of interactions of individual unit members to members of other units, thereby generating a molecular process model.
The following variables were included as explanatory variables in the final model: administration of Iloprost ("Ilo"), presence or absence of aggregates ("Aggregates"), measurements taken over time ("Time") as well as an interaction effect between Iloprost and presence of aggregates ("Interaction Test Ilo Aggregates").
Excipients in the formulation may be selected to reduce the propensity of a protein to aggregate through interaction with aggregation prone regions.
Both of them are defined by aggregating spatial interaction models based on Newton's law of gravitational force to represent the attraction force between two nodes in direct proportion to the attraction size and in inverse proportion to travel resistance.
Both the random and the same structured aggregates interactions were computed by summation.
Improper aggregate type and sizing, calcium chloride, and alkali-aggregate interactions are a few of the material problems.
