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These results strongly suggested that activity loss of ALDH3A1 was essentially attributed to aggregate formation.
The polyQ tract expansions result in conformational changes, eventually leading to aggregate formation.
This evidence suggests that protein aggregation is another aspect of SWCNT aggregate formation in biological settings.
Smith et al. studied huntingtin aggregation in an organotypic culture and found that minocycline at 30 µM inhibited aggregate formation.
As the plume cools, aggregate formation begins.
The mechanism of aggregate formation has been proposed.
This aggregate formation was shown to be reversible.
Elucidation of the specific mechanisms behind disulfide-linked aggregate formation may assist in designing processes that limit aggregate formation in cell culture, with implications for increased production.
The nanocrystal aggregate formation, and the surface uniformity and homogeneity were well documented.
Such transformation via aggregate formation has been observed for PDHS/SBA-15 nanocomposites [24].
Such aggregate formation and broader size distribution are characteristic of mechanically activated nanosized particles.
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