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Moreover, two aggregate sensitivity indices are determined, the first one is related to the orientation of the moving platform of the manipulator and the other one to its position.
A recent modeling study suggested that to be potentially cost-effective in terms of preventing mortality and disability, the aggregate sensitivity and specificity of multiplex assays for pre-XDR/XDR should at least be 88 and 96 %, respectively [ 27].
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Aggregated sensitivity, specificity, and positive and negative predictive values (PPV and NPV) were calculated.
We note that HSGE/GP-9 assays have been employed in several other contexts that, in aggregate, validate assay sensitivity and reproducibility.
The response distributions of each item for the sensitivity aggregate endorsement frequency showed all 8 items performing well (Table 2).
The drugs' effects on model parameters were somewhat stronger than their effects on behaviors in aggregate, highlighting the sensitivity of our model-based approach.
The results of the sensitivity aggregate endorsement frequency to examine the response distributions for each item reveal acceptable sensitivity of the instrument with 7 out of the 8 items performing well (Table 1).
Similarly, the IDI index was 0.008 (P < 0.001), indicating that an aggregate measure of sensitivity and specificity was superior for SAPS I score and NLR compared with SAPS I score only.
Bright dotted foci and hyperechoic stippled aggregates have 80% sensitivity and 75% specificity.
Only the presence of myotilin positive inclusions satisfied criteria to be considered suitable as a diagnostic test (<0.01% of fibres containing myotilin aggregates had a sensitivity of 100% and specificity of 82% for IBM − RV).
Since Castillo-Carranza [ 14] recently hypothesized that tau oligomers are the main toxic particle species in tauopathies, we analyzed the fluorescence data from the tau aggregation assay by cross-correlation (Fig. 1c) as cross-correlation detects oligomeric protein aggregates with higher sensitivity.
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