The results indicated that the bond strength of a mortar with CRA was higher than that of the natural aggregate reference mortar.
Corresponding characters described in [ 34] (LZ06#) included as an aggregate reference.
Samples are then added sequentially to the aggregate reference set.
In addition, we suggest the inclusion of an aggregate reference value for males and females combined.
We denote the exonic read count X for the test sample and Y for the aggregate reference.
This process of adding samples to the aggregate reference stops once the posterior probability stops to increase.
Therefore, additional refinements proposed by other CNV calling algorithms to improve calling accuracy could potentially be applied after ExomeDepth has identified the optimum aggregate reference set.
This differs from Swift which aligns images within each channel and then performs alignment on aggregate reference images in a single pass.
The initial tile length normalization performed in our method optimizes the generation of the aggregate reference set and minimizes the effect of GC content while CNV calling.
The main differences between these two programs are the implementation of exon length normalization (SubdivideGRange method) in ExomeCopy [ 13] and generation of aggregate reference set (select.reference.set method) in ExomeDepth [ 14].
