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On agar plates the invasive second stage juveniles (J2) of Heterodera cyst nematodes aggregate in response to localised 50 mM CaCl2 [2] and to root exudates [3] and also orientate to the latter [4].
Thus, an expanded set of proteins aggregate in response to arsenite exposure.
However, platelets produced from primary MK progenitor cells that were downregulated for Livin had a reduced ability to aggregate in response to AA and thus showed less functionality.
However, PLPs produced from LAMA-84 cells that were downregulated for Livin had a reduced ability to aggregate in response to epinephrine (P=0.0087) or AA (P=0.00016).
This PRP-based assay determines the propensity of platelets to aggregate in response to multiple concentrations of five agonists, and hence tests multiple platelet activation pathways simultaneously.
We found that many proteins that become insoluble with age also aggregate in response to iron supplementation, such as several ribosomal proteins, vitellogenins and heat shock protein 60.
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Epithelial cells polarize and differentiate into organotypic cell aggregates in response to cell cell and cell matrix interactions.
Although platelets from α2-deficient animals aggregated in response to collagen, they did so with prolonged lag time and lessened intensity.
Our results show no apparent toxicity of the formulated NPs, but a significant decrease of Aβ aggregates in response to Curcumin loaded NPs.
Interestingly, they demonstrated the in vivo formation of platelet aggregates in response to LPS [ 68].
These results demonstrate that hESC-PLTs together with human blood platelets can form aggregates in response to the appropriate stimulation.
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