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At 24 hours in the non-chelated model, only a few HGF (5 μM) and HaCaT (3 and 5 μM) cells appeared to aggregate, fragment, and begin showing dead floating cells, indicating apoptosis.
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When PrPTSE aggregates fragment into smaller units this increases the number of prion protein particles with seeding-active growth surfaces.
ICP analysis of radiodense fragments excised from ground meat packages from 13 deer identified lead in 25 (93%) of 27 samples; aggregate lead fragment mass per package averaged 17.2 mg (range±SD = 0.2 168±39.8 mg) or 0.03% of the lead component of bullet mass.
Ho et al. obtained an aggregate and fragment content of more than 50% by decreasing the light chain to heavy chain (LC:HC) ratio [ 37].
The 3C contact matrices were already aggregated at fragment size 40kb and were corrected for experimental bias according to [ 17].
Global model fragments, which aggregate the model fragments of local PPCs, make it possible to explain the behavioral change of the whole system focusing on the dominant principle/law.
ITLC showed the radiochemical purity to be 95% and 4% aggregates or fragments were observed with HPLC.
Both treated straw and model pulps were subjected to wet mechanical attrition, which caused separation of smaller fibril aggregates and fragments, significantly increasing enzyme hydrolysis rate.
The respective amounts of mAb monomer, aggregates and fragments were quantified by calculation of the peak areas detected by the ultraviolet (UV) detectors.
AOPPs are derived from oxidation-modified albumin (its aggregates or fragments), and are recognized as markers of oxidative damage to proteins, the intensity of oxidative stress, and inflammation [ 21].
DOI: http://dx.doi.org/10.7554/eLife.04288.004 At the normal growth temperature, large Sup35 aggregates are fragmented into smaller complexes by Hsp104 (Chernoff et al., 1995; Eaglestone et al., 2000; Ness et al., 2002; Satpute-Krishnan et al., 2007; Kawai-Noma et al., 2009).
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