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Yabroff et al examined aggregate cancer costs, so only reported on the cost of hospitalization because it was the primary driver of total cancer care costs.
The aggregate cancer risk for permethrin, based on estimated exposures for various scenarios and pathways, was found to be low (Macedo et al. 2007).
Unquestionably, the markers used in the MPS are associated with a poor aggregate cancer prognosis as demonstrated in multiple publications studying them individually or combined.
The U.S. EPA's most recent national-scale air toxics assessment was conducted for 1996 and estimates the annual aggregate cancer risk for 29 chemicals (U.S. EPA 2004b).
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However, aggregated cancer registry population counts, by year, closely match the national counts.
Aggregating cancer diagnosis in three groups according to prognosis and using this factor together with stage in the analyses showed a good fit of the models.
Tumor spheroids are aggregates of cancer cells that preserve native 3D cell-cell contact, mimicking the configuration of solid tumors (Weiswald et al. 2015).
Platelet aggregates and cancer cells duplets were excluded using size based gating.
There are several conventional methods for generating 3D aggregates of cancer cells, including NASA rotary cell culture systems, hanging drops, and culturing of cells using nonadherent surfaces [ 166– 168].
On the basis of haemalun eosin safran (HES) staining, only carcinoma cells were observed in colospheres, whereas no stromal cells were recognised, indicating that colospheres were structured aggregates of cancer cells and not merely globular fragments of tumour tissue.
It is recommended for the screening of women with an aggregate lifetime breast cancer risk of more than 20% [ 1].
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