Presumably, additional deregulations in downstream molecular pathways (breakdown of oxidative defense, eNOS uncoupling) occur with additional aggravation of conditions, diverting BK-induced signaling and allowing oxygen radical production to prevail.
The results suggested that HMGB1 plays an important role in aggravation of the condition in septic multiple organ failure.
The cause of treatment failure of the other 37 patients was an aggravation of general condition due to primary disease, and not due to any adverse effect.
A tent ICU near the epicenter can not only provide timely treatment to the victims, but also avoid the risks of aggravation of patients' condition during the evacuation [ 27, 28].
In a wide range of diseases, secondary damage to the brain or other organs follows the initial impact and may be responsible for aggravation of disease condition or clinical state, in particular neurological morbidity and/or mortality [ 4- 11].
Up to the early 2000s the re-grading of countries in the aftermath of a negative event or in the wake of debt-servicing problems was seen as a cause of a further aggravation of economic conditions for the borrowing countries even though conditions were clearly improving (Korea and Thailand, 1997; Uruguay, 2002).
Rapid aggravation of respiratory conditions required endotracheal intubation and assisted ventilation.
This aggravation of labour conditions has started a fatal circle: more and more German physicians are leaving the country, mostly to work in the U.K. or Scandinavian countries where they find better working conditions [ 1, 2].
Based on the anti-inflammatory function(s) of HCC, Chang et al., suggest that this protein may play an important role in the protection of normal sinus mucosa, and also in the prevention of aggravation of inflammatory conditions that occur in chronic sinusitis [ 11].
While our findings are consistent with the oxidative stress/inflammatory mechanistic hypothesis, our data do not support the hypothesis that particles promote anxiety through induction or aggravation of medical conditions, as there was no difference in the association by whether or not people had major medical comorbidities.
The inspection is made for the purpose of observing the degree of aggravation of their instantaneous condition in relation to their designed condition.
