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Contributions of E. coli and other gut bacteria to the aggravation of colitis were shown earlier in mono-associated germ-free IL10-/ and IL2-/ mice [27]-[29 [27]-[29the curative effects of antimicrobial therapy [15], [30], [31].
Early discontinuation, mostly due to aggravation of colitis, occurred twice as frequently in placebo-treated patients.
As expected, we could demonstrate that the elimination of Treg from mice with intact mucosal homeostasis led to the onset and aggravation of colitis.
Similar(57)
To determine whether TLR2 or TLR4 may be involved in the aggravation of acute colitis, we compared macroscopic signs of disease in C57BL/10 wild-type (wt) mice and animals lacking TLR2, TLR4, or both (Figure 1).
We found that TLE prevents LPS-induced proinflammatory gene expression by blocking NF-κB signaling, through aggravation of DSS-induced colitis by enhancing epithelial cell apoptosis following injury.
NSAIDs inhibit colonic prostaglandin synthesis, leading to the development of colitis and the aggravation of preexisting intestinal diseases.
However, the role of nonsteroidal anti-inflammatory drugs (NSAID) in colitis is controversial, and aggravation of disease due to these compounds has been described.
Aggravation of postcardioversion atrial dysfunction by sotalol.
Exercise should be individually tailored, to prevent injury and aggravation of the osteoarthritis.
Dealing with the pain and aggravation of a broken bone or burst appendix isn't easy.
DR. HORN: To what circumstances was this aggravation of the German-Polish situation to be attributed?
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