Sentence examples for aggravation of cell from inspiring English sources
This demonstrates an increase of apoptotic procedure, which confirms the aggravation of cell injury after reperfusion in cells subjected to ischemia.
In hepatocytes, in which no noticeable aggravation of cell injury was seen in the presence of glucose, endogenous glucose from glycogenolysis is likely to be available for metabolism also during incubation in glucose-free KH buffer.
Vero-B4 kidney cells showed a massive aggravation of cold-induced cell injury when stored at 4°C in RPMI 1640 cell culture medium, as compared to other cell culture media or KH buffer, and the combination of glucose, low calcium and high phosphate concentrations appeared to account for this phenomenon.
Cold storage in this modified KHG resulted in a similar aggravation of cold-induced cell injury as seen in RPMI 1640.
The aggravation of cold-induced cell injury by the triple combination seen here is thus likely to be caused by several interacting mechanisms: during cold storage, iron-dependent ROS formation is further increased due to both, the low Ca2+ concentration and simultaneously increased iron redox-cycling fostered by glucose via NADH availability.
Similar aggravation of IFNγ+CD4+ T cells is to blame for TB IRIS development in a subset of ART-treated, HIV- and Mtb-coinfected people.
Acute circulatory failure is found in 20% to 65% of patients with heatstroke and has been implicated in the aggravation of tissue injury and cell death [ 12, 13, 16, 31, 32].
Similar aggravation of Mtb-specific IFNγ+CD4+ T cell responses is to blame for TB IRIS development in a subset of HIV- and Mtb-coinfected people.
Another potential complication of acetazolamide administration is an aggravation of hypercapnia because of red blood cell CA inhibition and impaired CO2 transport [ 46].
The ischemic cascade leads to dysregulation of brain function and homeostasis due a profound oxidative stress and prominent subsequent inflammation, both of which lead to cell death and aggravation of tissue damage [ 4].
The impact of the high glucose-induced increase in miR-133a on insulin biosynthesis rates was not dramatic, but this mechanism may act in synergy with other high glucose-induced suppressive mechanisms leading to beta-cell failure and aggravation of Type 2 diabetes.
