Sentence examples similar to aggravating substantially from inspiring English sources

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This may be related to the relative stability of the glucokinase-related β-cell defect, as insulin secretion in MODY2 subjects does not seem to aggravate substantially over time.

"I believe it aggravates the problem substantially," he said.

The sentencing starting point for a murder committed by a child was 12 years' detention, Haddon-Cave said, but their case was "substantially aggravated" by the fact that it was a double murder, that their victims were asleep and must have "suffered terribly" in the moments before their deaths.

Lack of PD-1 substantially aggravated the pathological phenotype of the PLPtg mutants compared to genuine PLPtg mutants, whereas the PD-1 deletion alone did not cause alterations in the CNS.

Moreover, the overexpression of Aurora-A substantially aggravates the effect of irradiation, when compared to cells expressing GFP alone.

This is re-confirmed by our finding that smoking substantially aggravated TB mortality risks among those with TB history (from HR = 4.75 to HR = 10.10).

In our current meta-analyses, frequency of ferritin deficiency increased by twofold in patients at 6 months after surgery, and this trend became substantially aggravated at 24 and 36 months.

Where the human impact model already shows currently restricted metapopulation development, climate change is projected to aggravate this persistence perspective substantially.

We've already seen one dramatic example of storms aggravating an existing food crisis this year in Haiti, where the numbers of malnourished children coming to UNICEF-supported nutrition centres rose substantially in the wake of the storms there".

It is very aggravating.

But it was aggravating.

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