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"aggravating effect" is correct and can be used in written English
It usually refers to a situation that makes something else worse. For example, "The increasing cost of living has had an aggravating effect on poverty levels."
Exact(39)
Surprisingly, CftrΔF508/ΔF508/Kcnn4−/− mice survived significantly better than the CftrΔF508/ΔF508 mice (Fig. 1A), consistent with the idea that Kcnn4 is indeed a modifier gene for CF but suggesting an ameliorating effect of its inactivation rather than the aggravating effect expected from a straightforward mechanism involving its role in anion secretion.
Therefore, aggravating effect of examined polymorphism in MOH patients could be driven by its proneness to develop an impulsivity dyscontrol, the cornerstone of any substance abuse disorder.
On the other hand, perceived unpreparedness and report of recent testing showed aggravating effect on refusal of PIHT.
On the other hand, it showed adjusted aggravating effect for perceived unpreparedness to undergo testing [AOR (95% CI) = 1.86 (1.57–2.21)] and perceived clinical severity of HIV/AIDS [AOR (95% CI) = 1.67 (1.06–2.66)].
However, as mentioned above, this study aims to examine whether predictors modify (further potentiate or limit) the aggravating effect of the procedure; as a result it is the change (gradient) that had to be modeled.
The loss of touch response in expanded-polyQ nematodes can be manipulated by genetic means, as exemplified by the protective effect of sirtuin overexpression and aggravating effect of loss-of-function in the sir-2.1/SIRT1 daf-16/FOXO cell survival pathway [ 14].
Similar(21)
In order to test if the disease aggravating effects observed during early treatment with tamoxifen were indeed due to the ablation of BDNF, we performed treatment studies with glatiramer acetate.
It was anticipated that Fxr deficiency could aggravate effects of the model hepatotoxic compound cyclosporine A (CsA).
Animal research has not been conducted on the combined effects of RCF and granular, low-biosoluble particles such as TiO2, which can aggravate effects of inhaled fibers.
Excessive cash release for developmental projects is aggravating the effect of corruption on donor funded projects.
Thus Ca2 + drastically potentiates the effect of free fatty acids possibly due to the formation of an ion-pair that would increase fatty acid concentration in the membrane, aggravating its effect on complex I [43].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com