The phrase "aggravates the development of" is correct and usable in written English.
It can be used when discussing factors that worsen or hinder the progress of a particular process or condition.
Example: "The lack of funding aggravates the development of new technologies in the field."
Alternatives: "hinders the progress of" or "impedes the advancement of".
But with the increase in the pozzolanic reaction, the self desiccation effect coupled with the increase in disjoining pressure could probably have aggravated the development of micro cracks.
IL-17 and IL-22 play a dual role: on the one hand, they stimulate the epithelium to produce antimicrobial peptides and proteins, and mucus-associated molecules to clear the pathogen and tumor cells to maintain homeostasis of the mucosa; on the other hand, they may aggravate the development of obesity-related asthma and COPD.
The presence of coccidia might have aggravated the development of lesions in the bursa caused by IBDV.
We demonstrate that lack of sclerostin aggravated the development of OA in mice submitted to joint instability as a result of disrupted anabolic/catabolic balance.
Nevertheless, ICU patients have several risk factors for AKI, including hypovolemia, shock, use of diuretics or contrast medium and the presence of chronic kidney disease prior to ICU admission [ 31], and aminoglycosides could further aggravate the development of renal dysfunction in this population.
The spread of infections in healthcare environments is a persistent and growing problem in most countries, aggravated by the development of microbial resistance to antibiotics and disinfectants.
We suggest that SLE is the net result of an imbalance between these two systems, which is aggravated by the development of autoreactive antibodies, leading to the leakage of immune complexes from the circulation and the triggering of inflammation in the vessel walls and in the tissues.
We cannot even determine the cause of some diseases and do not know how to control them, thus aggravating the situation and hindering the development of aquaculture.
TNF-α perhaps is an initiator which can induce more cytokines such as IL-6 and IFN-γ, whicancaggravateate liver injury and initiate the development of ALF, and the disruption of TJ intestinal.
These first established findings suggest that IL-17 activation may be involved simultaneously in both aggravating intestinal inflammation and promoting the development of rapidly progressive IgAN in patients with Crohn's disease.
