Insulin resistance may aggravate gradually in those Japanese subjects together with metabolic changes, such as hyperglycemia and dyslipidemia, on the presence of the TNF 308 G/A polymorphism.
The erosion of the landward slope was then gradually aggravated followed by entire failure within a couple of minutes.
Severe microscopic damages occurred after approximately 200 FTCs and the freeze-thaw damage were gradually aggravated afterwards.
Air pollution gradually aggravated, which accelerates the demand of clean energy (in particular clean natural gas) because of its abundant storage worldwide.
It is the escalation of a series of assessment errors, which used force as a political practice and gradually aggravated the problems and intensified various conflicts.
The major pathogenic factors of HD might not disappear with the disease course, but the condition might gradually become aggravated; thus, active treatment intervention measures should be performed.
4 A 58-year-old woman had gradually aggravating dysphagia for 5 years.
She was diagnosed with "costal chondritis" at the local hospital and treated with corticosteroid (local blockade) and vitamin B12 (subcutaneous injection), but the pain was gradually aggravating; she experienced sternocostal pain of both sides and vertebral pain.
It usually comes on gradually and is aggravated by physical activity.
