Sentence examples for aggravate the development from inspiring English sources

IL-17 and IL-22 play a dual role: on the one hand, they stimulate the epithelium to produce antimicrobial peptides and proteins, and mucus-associated molecules to clear the pathogen and tumor cells to maintain homeostasis of the mucosa; on the other hand, they may aggravate the development of obesity-related asthma and COPD.

Nevertheless, ICU patients have several risk factors for AKI, including hypovolemia, shock, use of diuretics or contrast medium and the presence of chronic kidney disease prior to ICU admission [ 31], and aminoglycosides could further aggravate the development of renal dysfunction in this population.

But with the increase in the pozzolanic reaction, the self desiccation effect coupled with the increase in disjoining pressure could probably have aggravated the development of micro cracks.

Dyslipidemia in combination with inflammation initiates and aggravates the development of atherosclerosis and CAD [ 1].

The presence of coccidia might have aggravated the development of lesions in the bursa caused by IBDV.

We demonstrate that lack of sclerostin aggravated the development of OA in mice submitted to joint instability as a result of disrupted anabolic/catabolic balance.

This may aggravate the growth retardation.

Climate change in the region will have important negative consequences for humans and ecosystems, especially due to heat stress and reduced water resources; and population growth and economic development may aggravate the situation.

But the project, which needs approval from Beverly Hills officials, has already provoked some nearby residents who fear that the development could further aggravate the area's considerable rush-hour traffic woes.

The spread of infections in healthcare environments is a persistent and growing problem in most countries, aggravated by the development of microbial resistance to antibiotics and disinfectants.

Greenwerkz owner Dan Rogers is understandably aggravated at the development, especially since he deliberately complied with the regulations that he was ultimately forced to shut down for violating.