The phrase "aggravate pathology" is correct and usable in written English.
It can be used in medical or scientific contexts to describe the act of worsening or intensifying a disease or condition.
Example: "Certain lifestyle choices can aggravate pathology in patients with chronic illnesses, leading to more severe symptoms."
Alternatives: "exacerbate the condition" or "worsen the disease".
We show here that TLR3 regulates host immunity and the loss of TLR3 aggravates pathology in Chikungunya virus (CHIKV) infection.
Disruption of the network that maintains this protein homeostasis (proteostasis) leads to cellular dysfunction and causes or aggravates pathologies associated with aging and disease [ 1– 4].
The notion that mimicry between a self and a microbial peptide antigen can trigger or aggravate autoimmune pathology remains a popular hypothesis in autoimmunity research.
FGF8 can induce cartilage and bone degradation to cause the arthritis-like syndromes and possibly aggravate the pathology of OA.
Accordingly, future studies are required to investigate whether Cpn infections may aggravate AD pathology by stimulating the formation of Aβ plaques as has been suggested in atherosclerosis, a disease that is also characterized by pronounced local inflammation.
Vascular endothelial growth factor-A (VEGF) typically induces abnormal angiogenesis in the adult, thereby aggravating disease pathology and limiting utility of VEGF for therapeutic angiogenesis.
IL-17-producing CD4+ T cells or Th17 constitute a newly identified inflammatory cell population, which is critically involved in EAU [24], [25], [49] suggesting that rHsp65 aggravates EAU pathology by expanding antigen-specific Th1 and Th17 cells.
Whereas such detoxification by aggregation and deposition can be effective as a short-term strategy, it eventually becomes futile and then aggravates the pathology, particularly in humans with their long life-span.
It is therefore conceivable that we might have observed aggravated IML pathology in older tg mice.
Disruption of the cytokine-HPA axis feedback loop can aggravate inflammatory pathologies [ 11].
