Exact(10)
AGEs didn't change significantly the viability of Ana-1 macrophages within 25-100 mg/L AGEs concentration range for 3,6,12 and 24 h incubation.
Enzyme-linked immunosorbent assay was performed to quantity AGEs concentration in serum according to the reported method [ 14].
Despite the small number of subjects enrolled, the present findings have clearly demonstrated a significant decrease of serum AGEs concentration in CSU patients.
With the increase of AGEs concentration, the cell viability decreased progressively and reached a lowest level at AGEs 100 mg/L.
We aim to test whether chronic inflammation manifested by activated acute phase response may provide a mechanism for increased serum AGEs concentration in CSU.
It seems unlikely that diet contributes to lower serum AGEs concentration in CSU patients, because there have not been significant differences in the dietary AGEs intake between the two groups.
Similar(50)
With the increase of AGEs concentrations, the presence of autophagic vacuoles became progressively prevalent.
There are some mechanisms, which may account for lower circulating AGEs concentrations in CSU.
CSU is not associated with increased circulating AGEs concentrations, despite the enhanced systemic inflammatory response.
Secondly, it might be interesting to hypothesize that increased vascular permeability may partially contribute to lower serum AGEs concentrations.
CSU is not characterized by increased circulating AGEs concentrations, despite the enhanced systemic inflammatory response associated with acute phase response.
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