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The aim of this work was to study (a) the alterations in PDE3B activity and phosphorylation state in response to agents of relevance for insulin secretion as well as (b) the expression and activity of selected PDEs in human pancreatic islets.
However, given the vast number of potential POPS, we did not have the ability to assess all agents of relevance.
Owing to the vast number of potential persistent organic pollutants, we did not have the ability to assess all agents of relevance.
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Antibacterial agents are of relevance to a number of industrial sectors including environmental, water disposal, food, synthetic textiles, packaging, healthcare, medical care, as well as construction and decoration.
Unlike the hindlimb muscles, the diaphragm of mdx mice undergoes progressive deterioration of muscle structure and function and is therefore a preferred muscle when examining the efficacy of potential therapeutic agents of clinical relevance [ 5- 7].
Surveillance should continue for this infective agent of potential relevance for numerous species, including humans.
With the introduction of targeted agents, the relevance of prognostic and predictive markers in patient selection has become increasingly relevant.
The identification of species other than C. hominis and C. parvum that infect humans, and the transmission routes of such agents, has relevance for better understanding of the epidemiologic features of cryptosporidiosis.
Even though the micronuclei induction was not as high as it is with benzene or other well-established clastogenic agents, these lesions could be of relevance in a prolonged exposure regime or in a combined exposure with a clastogenic agent which is possible in a polluted environment scenario.
Invasive NTM disease in HIV-infected populations in sub-Saharan Africa demands more attention in terms of identification of etiologic agents, clinical relevance, and management.
As a consequence, the identification of the molecular target of autoantibodies might be of relevance in designing new antitumor agents.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com