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The phrase "agents of epidemic" is correct and usable in written English.
It can be used in discussions about the causes or factors contributing to the spread of an epidemic, such as in public health or scientific contexts.
Example: "The researchers identified several agents of epidemic that contributed to the rapid spread of the disease in the community."
Alternatives: "epidemic agents" or "causes of the epidemic".
Exact(5)
Human noroviruses are the leading causative agents of epidemic and sporadic viral gastroenteritis and childhood diarrhoea worldwide.
Noroviruses are common etiologic agents of epidemic gastroenteritis.
To the Editor: The agents of epidemic cholera are Vibrio cholerae toxigenic serogroups O1 and O139.
Body lice are vectors of Rickettsia prowazekii, Borrelia recurrentis, and Bartonella quintana, the etiological agents of epidemic typhus, relapsing fever, and trench fever, respectively.
Head, body, and pubic lice (genera Pediculus and Pthirus, respectively) parasitize millions of people each year and Pediculus species are important in human epidemiology, serving as vectors of the causative agents of epidemic diseases such as trench fever (Bartonella quintana), relapsing fever (Borrelia recurrentis), and louse-borne typhus (Rickettsia prowazekii; [ 49]).
Similar(55)
Experimental infection of chimpanzees with the Norwalk agent of epidemic viral gastroenteritis.
The genetic mechanism of membrane assembly in Rickettsia prowazekii, the causative agent of epidemic typhus, is unknown.
Neisseria meningitidis (Nm) is the etiologic agent of epidemic bacterial meningitis and rapidly fatal sepsis throughout the world.
V. cholerae O1, the causative agent of epidemic cholera, secretes a 32-kDa zinc-containing hemagglutinin protease that may play a role in the pathogenesis of cholera.
The obligate intracellular bacterium, Rickettsia prowazekii, is the causative agent of epidemic typhus, a louse-borne disease usually associated with non-hygienic conditions arising in crowded human populations during war, famine, and as a result of extreme poverty.
All members of the genus Rickettsia (Rickettsiales; Rickettsiaceae) are obligate intracellular parasites of eukaryotes [1], with some species that are pathogenic and are known to cause harmful diseases in humans, e.g., R. prowazekii, the causative agent of epidemic typhus and R. rickettsii, the agent of Rocky Mountain spotted fever [2].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com