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The development of new 68Ga-based molecular imaging agents and subsequent clinical translation would be greatly facilitated by simplification of radiochemical syntheses.
This improves the usability of the protein since reducing agents and subsequent laborious buffer exchanges can be avoided.
1– 5 The next goal should be remission without the use of biological agents and subsequent drug-free remission.
Studies to examine the mechanistic pathways involved in developmental exposure to environmental agents and subsequent increased susceptibility to adult onset disease (developmental imprinting).
For example, in HT29 cells growing anchorage dependently, increased exposure time to gemcitabine or camptothecin resulted in increased cytotoxicity of the chemotherapeutic agents as single agents and subsequent reduced potentiation by V158411.
When microcirculation of tumours is disrupted with angiogenesis and leaky capillary membranes, there is rapid accumulation of contrast agents and subsequent enhancement of tissues that is greater than that of similar normal tissue [ 2].
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The formation of permanent waves in the beauty treatment of hair is based on partial reduction of the disulfide bonds of hair keratin by thioglycol, or some other mild reducing agent, and subsequent oxidation of the sulfhydryl groups (−SH) in the reoriented hair to disulfide bonds (−S−S−) by exposure to the oxygen of the air.
The preform was fabricated by pyrolysis of cellulose fibres used as a pore-forming agent and subsequent sintering of alumina particles.
For example, Ramakrishna Matte et al. reported the insertion of MoS2 and WS2 with lithium by using n-butyllithium in hexaneas the intercalation agent, and subsequent exfoliation in water with ultrasonication to yield single-layer materials [54].
Moreover, chemical amine functionalization of the silica network surface of the hybrid polyHIPEs was demonstrated using a silane coupling agent and subsequent visualization by reaction with fluorescein isothiocyanate (FITC).
It can effectively be achieved by: i) the introduction of a longer polyethylene glycol chain spacer, or ii) the presence of a positive charge, known to favour renal elimination, or iii) attachment of a chelating agent and subsequent labelling with a radiometal.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com