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A new agent was defined as a prescription filled with no evidence of a previous prescription for that agent in the prior 9 months.
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Among patients with RI, we determined the number and proportion using any nephrotoxic agents, IV BP, and IV BP plus another nephrotoxic agent in the 12 months prior to and 12 months after the lowest recorded eGFR.
Approximately one-quarter (2760) of patients used a nephrotoxic agent in the 12 months prior to the bone metastasis diagnosis and 69% of patients used such agents at any time thereafter.
No patient had received hormone drugs or other immunosuppressive agents in the last six months prior to this study.
The coeliac disease patients' consumption of pharmaceutical agents in the year prior to and following the diagnosis is shown in Table 3.
A practical solution for increasing the sensitivity of LFA is to concentrate the target agent in a solution prior to the detection step.
Eligibility also included the prescription of at least one oral glucose-lowering agent (OGLA) in the year prior to enrollment.
Thus, despite its limitations, this study provides supportive evidence to pursue additional studies of lebrikizumab as a potential novel therapeutic agent in asthma prior to embarking on large proof-of-concept studies.
Data regarding delay between index culture and initiation of therapy, whether therapy was started before cultures were known to be positive (defined as empiric therapy), antifungal agents used, Candida species found on the index culture, and antifungal agents received in the month prior to the index culture were recorded.
A novel approach is the use of stoichiometric or catalytic bioscavengers for detoxification of nerve agents in the systemic circulation prior to distribution into target tissues.
To evaluate the robustness of our observations, we evaluated "any use" of antidiabetic drugs in a sensitivity analysis (either as monotherapy or in combination with other agents) in the 90 days prior to the index date in our multivariate models.
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