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With the development of more specific and well tolerated second generation TKIs which inhibit VEGF signaling, the prospect of applying these agents in combination with anti-resorptive agents holds significant promise for the prevention of bone metastatic disease.
The dominant owners are principals rather than agents; they hold significant stakes, rather than small, fragmented positions.
She saw a Border Patrol agent holding a gun.
Real estate agents today say porches still hold significant allure, particularly for the nostalgia-seeking homebuyer who remembers childhood summers sitting on cold flagstones playing cards with a warm breeze wafting through the screen.
Agents that inhibit Hsp90 function hold significant promise in cancer therapy.
Our findings suggest that the N-hydroxycinnamamide/SA hybrids may hold significant promise as therapeutic agents for the intervention of human cancers.
Even though two recent phase 3 clinical trials of fostamatinib in RA were a disappointment, other agents that target the B-cell receptor signaling pathway hold significant promises in treating autoimmune diseases [ 88].
The practice of medical tourism holds significant implications for the airlines that transport patients and also travel agents who do bookings for patients not using the services of facilitators/brokers.
Inhibiting key players in tumor angiogenesis such as VEGF and VEGF receptor7 holds significant potential for treatment of cancers; however, a limited number of patients respond to antiangiogenic agents.
Exploring new biological targets, specifically those overexpressed in stroma cells, holds significant potential for the design of specific nanocarriers to attain homing of therapeutic and imaging agents to the tumor.
a project or unit owned by an entity in which the agency or its officers, employees or agents hold a significant direct or indirect interest and which has among its purposes the ownership or management of affordable housing.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com