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The specific TwinsUK sample presented here represents a subsample recruited to study ageing traits in females.
As is the case in twin studies of many ageing traits, most of the best models were AE models, and the estimated effect of shared environment was minimal.
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In this article, the advantages of twin designs are described, followed by research findings illustrating the importance of both genetic and unique environmental factors in brain aging traits.
Here, we review our current understanding of lncRNAs that control the development of aging traits.
Aging traits are governed through changes in subsets of expressed proteins.
Furthermore, experimental evidence in mice indicates that caspase-2 deficiency enhances aging traits [ 28]; our data indicate down regulation of caspase pathway in aging fibroblasts.
Fish and fishless populations differed significantly for all instar-specific body sizes, instar-specific offspring sizes, and age traits measured (Table 1 and Fig. 1A,C,D).
Recent human genetic epidemiological studies suggest that insulin or IGF-like signaling is associated with human aging traits including longevity [ 28, 29].
The ReproGen Consortium was formed by more than 30 studies in the US and Europe to investigate the genetics of reproductive aging traits [ 10, 11].
A common polymorphism near the telomere maintenance gene TERT has been associated with several cancers, but relationships with other aging traits such as physical capability have not been reported.
We previously used longitudinal studies to demonstrate that multiple somatic aging traits, including coordinated body movement span, pharyngeal pumping span, and life span, are positively correlated in self-fertile C. elegans hermaphrodites (Huang et al. 2004).
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