Sentence examples for ageing phenotype of from inspiring English sources

Still, deletion of mitochondrial DNA exacerbates the premature ageing phenotype of psd1Δ indicating that mitochondria are at least partially functional in psd1Δ.

We confirmed the premature ageing phenotype of the PSD1 and PSD2 knock outs by clonogenic survival plating and assessed the PE- and PC-abundance at day 3 of ageing by HPLC-assisted analyses of lipid extracts.

Data described above might underlie the aging-associated decrease in the proliferation rate of bmMSCs, an aging phenotype of mammalian bmMSCs [ 3, 30, 31].

All these concepts postulate an "accelerated aging" phenotype of RBCs during malaria that leads to clearance of RBCs by unspecific mechanisms.

These progressive changes represent additional features of the accelerated aging phenotype of VDR KO mice, and are distinct from the effects of VDR ablation during puberty and pregnancy.

In addition, we compared the aging phenotype of captive lines derived from two habitats differing in aridity and found that age-related cognitive deficit was influenced by the geographic origin of the captive lines.

In this present study, we used global gene expression profiling to gain further insight into the molecular mechanism leading to the segmental premature aging phenotype of the XpdTTD mutant mice harboring defects in NER and general transcription.

Thus, the premature aging phenotype of K6001-B7 is not galactose-specific.

In agreement with this idea, a temperature shift is sufficient to revert the aging phenotype of PHB depletion.

The accelerated aging phenotype of RA T cells includes shortening of telomeres, loss of CD28 and reduced efficiency of DNA repair mechanisms [ 46- 49].

The premature aging phenotype of Klotho -/- mice has been attributed to the absence of Klotho mediated suppression of the Insulin/IGF-I pathway [ 7, 12].