Patients with CD can be classified by Montreal or Paris classification regarding age of onset, localization, behavior, and growth.
Age of peak localization was defined as the Moment, i.e. the age when extra mid-cell fluorescence reached its maximum.
A decision tool based on three questions (age of child; localization of bruise during the initial 72 hours of patient's admission; and confirmation of accident in public setting) identified abused children among children aged 0 to 4 y admitted to a Pediatric Intensive-Care Unit, with a sensitivity of 97% (95% CI: 84-100) [ 31].
At the end of the treatment (20 weeks of age), localization of vector delivery was confirmed by luciferase activity after ip injection of 100 µl (40 mg/ml) luciferin (Gold Biotechnology, St . Louis MO) and luminescence was imaged by an in vivo luminescence imager (Xenogen IVIS® imager using living® image software, Alameda, CA).
At 12 weeks of age, the localization of lipid droplets at both the tubular and glomerular level was similar in POKO and ob/ob kidneys (data not shown).
As concerns the allocation of clinico-pathological characteristics among the 4 groups, all 21 parameters were equally distributed in terms of age, tumor localization, type of metastasis, histology, and cardiopulmonary status (Table 1).
Epilepsy is defined as recurrent, self-limited and unprovoked seizures, and can be classified according to the age of onset, the localization of seizure origin (focal or generalised), and aetiology.
The parents were asked to report the age at which the child achieved motor milestones, the fracture incidence, and the age and localization of the first surgical intervention.
After interdisciplinary discussion a surgical treatment approach had been excluded due to comorbidity, age, or localization of the tumour.
We (scientists and physicians engaged in pharmacogenetics and genomics) have learned and repeatedly taught the following: analyzing inherited genetic variation has the big advantage that analysing the genome of one cell of an organism provides reliable information on all the other cells independent of age, tissue localization or environmental factors.
