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The mean (± SD) age at analysis was 43.5 ± 15.3 years and 35 ± 9.9 years for Tunisian and Turkish controls, respectively.
Collectively, these data indicate that BPA exposure decreases sex steroid hormone levels in male rodents, but strain and species, as well as other confounders (e.g., time, route of exposure, age at analysis), may modulate the sensitivity to BPA effects.
In the group of 14 children enrolled for the study of antigen-specific memory B cells, the mean age at analysis was 6.8 years (range 4 12), nine were males and five females.
The period of 3.5 weeks was designed for potential radiation-induced HR events to occur and to adjust for previously determined age-related increases in HR events (both continuously exposed animals and acutely exposed animals were of the same age at analysis).
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For survival and age-at-onset analysis, the Log-Rank test was performed.
In the Cox's regression models, time between first breast cancer and start of follow-up (to adjust for survival bias), year of diagnosis first breast cancer, age at mutation analysis, age at diagnosis first breast cancer, BPO, surgery (breast-conserving surgery or mastectomy), chemotherapy, radiotherapy and stage of first breast cancer were evaluated as confounders.
> -wrap-foot> ate at onset analysis was also performed in the Flanders Belgian GRN founder family, an extended FTLD pedigree segregating the GRN IVS1 + 5G > C null mutation and in which a wide range in onset age was previously reported (Cruts et al., 2006; Brouwers et al., 2007).
To verify the over-expression of Tph1 and Tph2, islets were isolated from Control and pBmpr1aKO mice at 3 months of age at which transcriptomic analysis was performed.
To create populations with an approximately equal average age at death, the analysis was performed on slightly younger age-groups for studies with a longitudinal design as compared to the cross-sectional studies (35 79 years).
For the analysis of age at lateral displacement and the analysis of range of motion (ROM) at time of lateral displacement, these four children were excluded (Table 3).
The dose of inhibitor is abbreviated as "L" for low dose and "H" for high dose which is preceded by the age of the animal at analysis.
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