96 However, other reports have also noted a negative association between age and proliferation of subcutaneous preadipocytes, which may explain selective loss of subcutaneous adipose tissue with aging.
Multivariate analyses of the NKI dataset showed that the grade, the ER status, age, and proliferation were all significant and independent predictors of survival (Additional file 2, Supplemental Tables 8 and 9).
The expression of Prx I and Prx II correlates with astrocytic tumor features, such as grade and patient age and proliferation activity (Prx I), and accordingly with patient survival.
Since 12q24.31 gain did not associate with any of the other prognostic parameters, such as histology (INPC), stage, age and proliferation index (results not shown), our data suggest that it may have independent prognostic value in neuroblastoma risk stratification.
Other characters portray the impact of 9/11, the war on terror and post-traumatic stress disorder; the fear of Aids; the arrival of the technological age and the proliferation of the internet.
Since the end of the last ice age and the proliferation of humans across the continents, our agricultural methods, our cities, our energy production, our transportation networks, our plastics, and our atomic tests are radically altering the biological and chemical composition of the air, soil, and water and even leaving what some say will be a lasting impression on Earth's geology.
HJURP mRNA levels were significantly associated with estrogen receptor (ER), progesterone receptor (PR), Scarff-Bloom-Richardson (SBR) grade, age and Ki67 proliferation indices, but not with pathologic stage, ERBB2, tumor size, or lymph node status.
With age, the activation and proliferation response of aged muscle stem cells after injury declines as compared to young [ 14].
Prognostic factors such as tumour size, tumour grading, hormone receptor status, age, histology, ploidy and proliferation index are used to define subgroups of high-risk NNBC patients [ 1- 8].
All these results suggest that epigenetic reprogramming of genomic imprinting maintains the quiescence of Oct4+ epiblast/germ line-derived VSELs deposited in the adult body and protects them from premature ageing and uncontrolled proliferation (e.g., teratoma formation).
In summary, canine uterine adenogenesis was underway by 1 wk of age and prepubertal glandular proliferation was essentially complete by Week 6.
