The phrase "age alteration" is correct and usable in written English.
It can be used in contexts discussing changes or modifications related to age, such as in medical, cosmetic, or social discussions.
Example: "The study focused on the effects of age alteration on cognitive function in older adults."
Alternatives: "age modification" or "age adjustment".
With age, alterations in the expression of autophagy-related genes have been reported.
With advancing age alterations were mainly reported on T cell mediated immunity.
Cognitive alterations associated with DTI changes might be related with early age alterations during the neurodevelopment stages.
Recently, we have extended our studies to mammals and found that aging alteration by reducing IGF signaling protects mice from behavioral, pathological and biochemical phenotypes associated with AD-like disease (Cohen et al., 2009).
In C. elegans, loss-of-function mutations of the DAF-1/FOXO upstream kinases such as DAF-2 and aging alteration-1 (age-1) promoted DAF-16/FOXO protein translocation into the nucleus to activate or repress its target genes (Kenyon, 2005; Calnan and Brunet, 2008).
With aging, alterations of VSMC cytoskeletal proteins such as α-SMA and vimentin occur concomitantly with changes in VSMC migration rates [35].
Loss of mobility, medications, associated comorbidities, and rectal sensory-motor dysfunction are as important as gut aging alterations in causing constipation.
In particular, the risk to develop an ADR related to a negative drug drug interaction is increased in the elderly due to CNS ageing alterations and may be more relevant in Alzheimer patients (see the previous section).
Kawabuchi and colleagues (2001) provide insight into normal aging alterations in NMJs from their study of reinnervation of the crushed sciatic nerve in 64 rats (30 adult and 34 aged).
At this age, any alteration in dental aspects can have a negative impact on QoL [ 25, 27].
