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The phrase "against it when" is correct and usable in written English.
It can be used in contexts where you are discussing opposition or disagreement that occurs at a specific time or under certain conditions.
Example: "She was always against it when the proposal was first introduced at the meeting."
Alternatives: "opposed to it when" or "against it at the time".
Exact(60)
It had proved popular with Anonymous hacktivists, but many turned against it when its owner said he was considering removing "sensitive information".
"The government will win the vote of confidence, but the M.P.'s who are opposing the referendum will vote against it when they're asked to vote for its implementation".
But this very drive to consume the book turns against it when you are foiled by the frailty of its physical corpus.
Then I turned against it when we were shadowing the European exchange rate mechanism".
"There is no reason to legislate against it, when homosexual sex is already illegal.
The proudly independent vineyards are up against it when facing large, industrial-scale appellations.
His right knee was heavily braced, and he was having trouble pushing off against it when he served.
After backing it, the Lib Dems turned against it when unease among voters and clinicians grew earlier this year.
I'm against it when TV wants to make a celebrity out of someone who doesn't have the material.
"I railed against it when I was young, but as you got older you realised there were logical reasons.
You can't be for getting rid of Saddam Hussein when things look good and against it when times are hard".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com