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As in other previous iterative schemes, simulations show that after two iterations improvements are negligible, so IEC always performs only two iterations.
After two iterations from fragment 1, we were able to increase potency by greater than 500-fold to provide sulfonamide 13, a 78-nM JAK-2 inhibitor.
After two iterations of complete redevelopment cycles with five intermediate prototype systems generated, a much improved version of the tool, namely SimuSurvey R2, was developed.
This gain in production was attributed to just two amino acid substitutions, and it was isolated after two iterations through the two-tiered approach.
After two iterations Amiet׳s noise prediction is precise at high-frequencies, however generally overestimated in the frequency range where the airfoil is considered a compact noise source – acoustic wavelength comparable to the chord.
Convergence was reached after two iterations.
Similar(29)
Figure 6 shows the final BER perfotextance of all three iterative schemes considered in our study for 23% notextalized Doppler frequency after six iterations.
If we start the iterative procedure given in the proof of (iii) of Theorem 3.1, after five iterations, we obtain (3.32).
A modified iteration procedure implemented in this work gives convergence of the solution after three iterations.
It was found that numerical convergence was usually achieved after three iterations with 2% discretization.
The results show that the optimal die gap profile can be obtained after three iterations.
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