After screening of thousands of compounds, we identified Ponatinib as a BCLM inhibitor.
After screening of various immobilized biocatalysts, HPMC PVA:BCL was found to be a robust biocatalyst.
Neusilin® US2 was selected as an adsorbent after screening of various silicates.
The search yielded 272 citations of which 24 underwent full text review after screening of the titles and abstracts.
Using a random approach followed by site-directed and saturation mutagenesis, three beneficial amino acid mutations were found after screening of ca. 20,000 variants.
A mutant S63L/D232A with improved activity toward CNDE was obtained after screening of approximately 2500 clones from random-mutant libraries.
The optimization exercise was done using Face centered cubic design (FCCD) after screening of variables by L8 Taguchi orthogonal array design.
After screening of a library of more than 4000 colonies, about 15 positive colonies were analyzed, resulting in a higher concentration of trehalose than control.
After screening of the SSM-BSLA library in buffer and in presence of each of the three organic solvents, residual activity of BSLA variants (RV) and the residual activity of WT RWTT) were calculated.
The obtained T0 transgenic seedlings were grown in a paddy rice field after screening of tolerant-hygromycin and DNA sequencing according to our described methods (Jiang et al. 2014a, b).
However, after screening of different acids (Camphorsulfonic acid, TiCl4, BF3·OEt2, Proline) and bases (KOH, K2CO3, KO-t-Bu), no further improvement was realized to produce more trans isomer.
