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The model thus developed was validated using reactor data which was obtained by stepping the inlet HC concentration to zero after outlet reached equilibrium.
Growth factors have been reported in the bladder development and the remodeling of the bladder wall after outlet obstruction [ 35].
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Collagen and transforming growth factor- β expression protein increased after bladder outlet obstruction, and the expression of both returned to original levels after MSC transplantation.
Also, during the nights, excess water could be led to a pond built right after the outlet to be stored for day-time usage.
There is increasing evidence that ischemia/reperfusion is a major etiological factor in the progression of bladder dysfunction after partial outlet obstruction.
In addition, a predictive model for bioreactor design can be derived from the proposed model, after good outlet gas temperature estimation has been achieved.
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