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Therefore, we excluded the clinical trials having update information later than 14 month after completion date.
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Twelve of the 31 trials registered after the completion date in http://ClinicalTrials.gov were published after 2005 in journals proclaiming to adhere to ICMJE principles (data not shown).
We called a lawyer only after the completion date for our work had lapsed by months and the drainage problem became apparent.
30% of trials were registered incorrectly after their completion date.
First, 30% of the trials analysed were registered after the completion date.
The participating practices were contacted after the completion date to verify the documented outcomes and to explore the sustained impact of the completed PPDP process.
Trials with update information later than 14-month after the completion date were eliminated, which resulted in 320 and 302 trials for India and South Africa, respectively.
14 We were surprised to see that about a third of trials examined in our study were registered after the completion date; this kind of registration seems inappropriate or irrelevant and is a challenge to the credibility of the registers.
Figure 1 plots the patient's healthcare events from the OP, GP, and A&E datasets for a 2 year period (i.e. August 2008 to August 2010), which represents the timeline approximately one year before and one year after the completion date of the questionnaire by the patient.
Important limitations of solely relying on questionnaire data include reliance on accurate patient recall and that the healthcare events of interest may not occur within the limited recall period (e.g. 3 months), but just before the recall period or after the completion date of the questionnaire.
After publication of the AAC commentary and two years after the study completion date, the metrics were again changed in www.clinicaltrials.gov [ 32] adding back a metric on urinary tract infections and explaining the data on CLABSI could not be reported due to problems in standardizing the denominator.
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